As every year, the NVHG organizes a conference for all Dutch geneticists to connect, share knowledge, collaborate, and network. The NVHG aims to provide the latest advancements in genetics and genomics, from basic to translational research, both within and outside the Netherlands. This year, the NVHG celebrates its 75th anniversary, placing the field of genetics in the perspective of the past and future. How has the field evolved over the years, and what can we expect in the near future? What will its contribution be to improving health?