Study the spike protein from SARS-CoV-2 Variant P1, a CDC variant of concern, with this packaging mix for lentivirus pseudotyped with the P1 spike protein
- Based on SBI’s popular and highly cited pPACKH1 Packaging System
- Uses codon-optimized SARS-CoV-2 “S” protein from variant P1 in place of VSV-G envelope protein
- Spike protein mutations are L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I, V1176F
- Ideal for vaccine and antiviral efficacy studies under BSL2 conditions
- Package any 3rd-generation lentivector reporter of your choice, including SBI’s popular LentiLabeler reporters
| Cat. No. | Description | Size |
| CVD19-630A-1 | pPACK-SPIKE P1, SARS-CoV-2 “S” Pseudotype – P1 Variant – Lentivector Packaging Mix | 10 reactions |
| CVD19-635A-1 | pPACK-SPIKE P1, SARS-CoV-2 “S” Pseudotype – P1 Variant – Lentivector Packaging Mix | 25 reactions |
| CVD19-639A-KIT | pPACK-SPIKE P1 Combo Kit, includes Cat# CVD19-630A-1, plus PureFection Transfection Reagent (Cat# LV750A-1) and PEG-it Virus Concentration solution (Cat# LV810A-1) | 1 kit |
How It Works
pPACK-SPIKE is easy to use—simply co-transfect the pPACK-SPIKE Plasmids and your lentivector construct into 293TN producer cells or other lentiviral production cells, isolate pseudoviral particles with an optional concentration step, and conduct your studies.
