Do you need a tool to silence target gene expression?
OriGene offers a wide range near 500 genes of short hairpin RNA plasmids. OriGene uses a 29-mer short hairpin design for Hush-29TM shRNA plasmids, which has been demonstrated to be more effective than 21-mer designs with a guaranteed knockdown of ≥70%.
OriGene’s Custom shRNA Design Service are for the special needs outside our pre-designed shRNA products. Examples are
- shRNA targeting species other than Human, Mouse or Rat
- Integrate an effective siRNA oligo sequence into an shRNA vector
- Isoform-specific knock down
- Have shRNA constructs that target multiple species
- Reproduce a published result where shRNA sequence is available/disclosed
- A scrambled negative control is included.
- Lentiviral vector now available!
There are two modes of service with Exact-shRNA:
- Self-design: Customers specify the short hairpin sequences (stem and loop), choose a vector and OriGene constructs the plasmid.
- OriGene-design: Customers define the transcript sequence(s) and OriGene designs the shRNA (stem and loop) using their proprietary algorithm.
Contact us if you would like assistance in the design of your SHRNA constructs, or need more information
